NatraGel Cellenis – Injectable PRP Gel Filler

Autologous Platelet-Rich Plasma (PRP) Gel Filler

Overview

NatraGel Cellenis is a regenerative, autologous dermal filler created by thermally modifying the patient's own platelet-rich plasma (PRP) into a cohesive gel-like consistency. This technique produces a natural volumizing agent enriched with growth factors and cytokines that support tissue regeneration, collagen remodeling, and long-lasting dermal enhancement without the use of synthetic additives or cross-linked hyaluronic acid.

Mechanism of Action

Following venous blood collection and centrifugation, PRP is isolated and subjected to a controlled thermal process. This process denatures plasma proteins, resulting in a fibrin-rich gel with a dense scaffold structure. When injected into the skin, NatraGel acts as both a volumizer and a biostimulatory matrix. Platelet-derived growth factors—including PDGF, TGF-β, VEGF, and EGF—stimulate fibroblast activity, angiogenesis, and extracellular matrix production, thereby improving tissue quality and elasticity.

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Indications and Treatment Areas

NatraGel is ideal for patients seeking a fully natural, biocompatible filler solution. Common treatment areas include:

  • Tear troughs (under-eye hollows)
  • Nasolabial folds
  • Perioral lines
  • Cheek augmentation
  • Neck and décolleté
  • Fine lines and skin quality improvement
It may also be layered with traditional PRP injections to enhance skin texture and tone in areas of facial laxity or scarring.

Clinical Considerations

Because NatraGel is derived entirely from the patient's own blood, it poses no risk of allergic reaction or foreign body response. Results are typically softer and more gradual compared to traditional HA fillers, with continued improvement over weeks as neocollagenesis occurs. Mild swelling, redness, or bruising at the injection site are the most common side effects. The product is completely resorbable and metabolized naturally over several months.

Summary

NatraGel Cellenis offers a groundbreaking advancement in regenerative aesthetics—merging the volumizing capabilities of dermal fillers with the cellular rejuvenation potential of PRP. This 100% natural, autologous option is ideal for patients seeking subtle, safe, and biologically active aesthetic enhancement.

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